GGH and YTHDF3

Data Source:
BioGRID (affinity chromatography technology)

		GGH	YTHDF3
Description		gamma-glutamyl hydrolase	YTH N6-methyladenosine RNA binding protein 3
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Vacuole Cytosol Azurophil Granule Lumen Specific Granule Lumen Melanosome Extracellular Exosome Tertiary Granule Lumen	Cytoplasm Cytosol
	Molecular Function	Protein Binding Exopeptidase Activity Omega Peptidase Activity Gamma-glutamyl-peptidase Activity	RNA Binding MRNA Binding Protein Binding Ribosome Binding N6-methyladenosine-containing RNA Binding
	Biological Process	Proteolysis Response To Zinc Ion Response To Insulin Response To Drug Neutrophil Degranulation Response To Ethanol Tetrahydrofolylpolyglutamate Metabolic Process	Positive Regulation Of Translation Positive Regulation Of Translational Initiation Negative Regulation Of Type I Interferon-mediated Signaling Pathway MRNA Destabilization
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488)	Adult body size ( 32376654) Body size at age 10 ( 32376654) Breakfast cereal skipping frequency ( 31190057) Breakfast skipping ( 31190057) Chronotype ( 30696823) HDL cholesterol levels ( 32203549) Myocardial infarction ( 26708285) Smoking behaviour (cigarettes smoked per day) ( 30679032) Systolic blood pressure ( 30224653) Triglyceride levels ( 32203549)
Interacting Genes		2 interacting genes: LIG4 SGTB	2 interacting genes: FAF1 ZDHHC17
Entrez ID		8836	253943
HPRD ID		03299	08106
Ensembl ID		ENSG00000137563	ENSG00000185728
Uniprot IDs		Q92820	A0A024R7W5 A0A087WY31 B4DPX9 Q658Z6 Q7Z739 Q8N3V9 Q8NA80
PDB IDs		1L9X	6ZOT
Enriched GO Terms of Interacting Partners?
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