CREG1 and SERPINC1

Data Source:
HPRD (in vitro)

		CREG1	SERPINC1
Description		cellular repressor of E1A stimulated genes 1	serpin family C member 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Azurophil Granule Lumen Extracellular Exosome	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Plasma Membrane Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle
	Molecular Function	Transcription Corepressor Activity	Protease Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Heparin Binding Identical Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Regulation Of Growth Neutrophil Degranulation Negative Regulation Of Transcription, DNA-templated	Acute Inflammatory Response To Antigenic Stimulus Response To Nutrient Lactation Blood Coagulation Negative Regulation Of Endopeptidase Activity Post-translational Protein Modification Cellular Protein Metabolic Process Regulation Of Blood Coagulation, Intrinsic Pathway
Pathways		Neutrophil degranulation	Intrinsic Pathway of Fibrin Clot Formation Common Pathway of Fibrin Clot Formation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs			Ardeparin Fondaparinux Heparin Enoxaparin N-Formylmethionine SR-123781A Sulodexide Danaparoid Dalteparin Tinzaparin Nadroparin Copper Protamine sulfate Bemiparin Antithrombin III human
Diseases			Inherited thrombophilia
GWAS		Asthma ( 31959851) Blood protein levels ( 30072576 29875488)	Experiencing mood swings ( 29500382) Heel bone mineral density ( 30598549)
Interacting Genes		6 interacting genes: CAPN1 IGF2R RB1 RBL1 RBL2 TBP	6 interacting genes: F2 KLK1 KLK2 KLK6 PLG SDC2
Entrez ID		8804	462
HPRD ID		09897	00122
Ensembl ID		ENSG00000143162	ENSG00000117601
Uniprot IDs		O75629	A0A024R944 P01008
PDB IDs		1XHN	1ANT 1ATH 1AZX 1BR8 1DZG 1DZH 1E03 1E04 1E05 1JVQ 1LK6 1NQ9 1OYH 1R1L 1SR5 1T1F 1TB6 2ANT 2B4X 2B5T 2BEH 2GD4 2HIJ 2ZNH 3EVJ 3KCG 4EB1
Enriched GO Terms of Interacting Partners?
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