FPGT and PTGFR

Data Source:
BioGRID (two hybrid, two hybrid)

		FPGT	PTGFR
Description		fucose-1-phosphate guanylyltransferase	prostaglandin F receptor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Extracellular Region Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Catalytic Activity GTP Binding Fucose-1-phosphate Guanylyltransferase Activity	Prostaglandin F Receptor Activity
	Biological Process	Fucose Metabolic Process	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Parturition Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Response To Estradiol Response To Lipopolysaccharide Calcium-mediated Signaling Using Intracellular Calcium Source Negative Regulation Of Apoptotic Process Cellular Response To Prostaglandin D Stimulus
Pathways		GDP-fucose biosynthesis	Prostanoid ligand receptors G alpha (q) signalling events
Drugs			Travoprost Latanoprost Bimatoprost Dinoprost tromethamine Tafluprost Latanoprostene bunod
Diseases
GWAS		Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Menarche (age at onset) ( 27182965) Mental health study participation (completed survey) ( 31263887) Parental longevity (combined parental age at death) ( 29227965)	Bipolar disorder ( 22182935) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Lung function in never smokers (high FEV1 vs average FEV1) ( 26423011) Skin fluorescence in type 1 diabetes ( 27207532) Systolic blood pressure (alcohol consumption interaction) ( 24376456)
Interacting Genes			5 interacting genes: AGTR1 PTGDS PTGER1 PTGER2 PTGES2
Entrez ID		8790	5737
HPRD ID		06790	08988
Ensembl ID		ENSG00000254685	ENSG00000122420
Uniprot IDs		A0A0S2Z4P4 A0A0S2Z5C6 O14772	P43088
PDB IDs
Enriched GO Terms of Interacting Partners?
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