NAPA and SLC6A9

Data Source:
BioGRID (proximity labelling technology)

		NAPA	SLC6A9
Description		NSF attachment protein alpha	solute carrier family 6 member 9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Vacuolar Membrane Cytosol Plasma Membrane Membrane SNARE Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Extracellular Exosome Presynapse Postsynapse Glutamatergic Synapse	Endosome Plasma Membrane Integral Component Of Plasma Membrane Basal Plasma Membrane Postsynaptic Density Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane Integral Component Of Synaptic Vesicle Membrane Dense Core Granule Hippocampal Mossy Fiber To CA3 Synapse Parallel Fiber To Purkinje Cell Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane
	Molecular Function	SNARE Binding Soluble NSF Attachment Protein Activity Protein Binding Syntaxin Binding Protein-containing Complex Binding	Glycine Transmembrane Transporter Activity Glycine:sodium Symporter Activity
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Brain Development Regulation Of Synaptic Vesicle Priming Synaptic Vesicle Priming Neuron Differentiation Positive Regulation Of ATPase Activity Synaptic Transmission, Glutamatergic SNARE Complex Disassembly Apical Protein Localization COPII Vesicle Coating Membrane Fusion	Neurotransmitter Transport Glycine Transport Sodium Ion Transmembrane Transport Positive Regulation Of Hemoglobin Biosynthetic Process Positive Regulation Of Heme Biosynthetic Process Transport Across Blood-brain Barrier Glycine Import Across Plasma Membrane Positive Regulation Of Iron Ion Transmembrane Transporter Activity Positive Regulation Of Iron Ion Import Across Plasma Membrane Negative Regulation Of NMDA Glutamate Receptor Activity
Pathways		COPII-mediated vesicle transport Golgi Associated Vesicle Biogenesis COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network	Na+/Cl- dependent neurotransmitter transporters
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	Attention deficit hyperactivity disorder or cannabis use ( 30610198) Autism spectrum disorder or schizophrenia ( 28540026) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 29403010 32888494) Refractive error ( 32231278)
Interacting Genes		18 interacting genes: APP BNIP1 GNA12 GOSR1 GOSR2 HSPB1 NSF RTN4 SNAP23 SNAP25 STX12 STX1A STX4 STX5 STX7 STX8 TRPC3 VAMP8	3 interacting genes: GABRR1 PRKCA STX1A
Entrez ID		8775	6536
HPRD ID		04447	03010
Ensembl ID		ENSG00000105402	ENSG00000196517
Uniprot IDs		A0A024R0R9 P54920	B7Z3W8 B7Z589 P48067
PDB IDs
Enriched GO Terms of Interacting Partners?
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