ABCC3 and MKS1

Data Source:
BioGRID (affinity chromatography technology)

		ABCC3	MKS1
Description		ATP binding cassette subfamily C member 3	MKS transition zone complex subunit 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane	Cytoplasm Centrosome Cytosol MKS Complex Ciliary Basal Body
	Molecular Function	ATP Binding ABC-type Xenobiotic Transporter Activity Glucuronoside Transmembrane Transporter Activity ABC-type Glutathione S-conjugate Transporter Activity ABC-type Bile Acid Transporter Activity ATPase Activity ATPase-coupled Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity Icosanoid Transmembrane Transporter Activity	Protein Binding
	Biological Process	Drug Transmembrane Transport Bile Acid And Bile Salt Transport Canalicular Bile Acid Transport Glucuronoside Transport Xenobiotic Transport Transmembrane Transport Leukotriene Transport Anion Transmembrane Transport Transport Across Blood-brain Barrier	Cilium Assembly Ciliary Basal Body-plasma Membrane Docking
Pathways		Recycling of bile acids and salts ABC-family proteins mediated transport	Hedgehog 'off' state Anchoring of the basal body to the plasma membrane
Drugs
Diseases			Bardet-Biedl syndrome (BBS) Meckel syndrome (MKS); Meckel-Gruber syndrome
GWAS			Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Post bronchodilator FEV1 in COPD ( 26634245) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
Interacting Genes		2 interacting genes: MLH1 MTDH	2 interacting genes: DDX24 TMEM67
Entrez ID		8714	54903
HPRD ID		06826	07900
Ensembl ID		ENSG00000108846	ENSG00000011143
Uniprot IDs		O15438 Q86VN9	A0A0S2Z5Z2 B4DVC5 H0Y2S2 J3KSC6 Q9NXB0
PDB IDs
Enriched GO Terms of Interacting Partners?
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