ABCC3 and HLF

Data Source:
BioGRID (affinity chromatography technology)

		ABCC3	HLF
Description		ATP binding cassette subfamily C member 3	HLF transcription factor, PAR bZIP family member
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane	Chromatin Nucleus Nucleoplasm
	Molecular Function	ATP Binding ABC-type Xenobiotic Transporter Activity Glucuronoside Transmembrane Transporter Activity ABC-type Glutathione S-conjugate Transporter Activity ABC-type Bile Acid Transporter Activity ATPase Activity ATPase-coupled Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity Icosanoid Transmembrane Transporter Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Double-stranded DNA Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Drug Transmembrane Transport Bile Acid And Bile Salt Transport Canalicular Bile Acid Transport Glucuronoside Transport Xenobiotic Transport Transmembrane Transport Leukotriene Transport Anion Transmembrane Transport Transport Across Blood-brain Barrier	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Skeletal Muscle Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Rhythmic Process
Pathways		Recycling of bile acids and salts ABC-family proteins mediated transport
Drugs
Diseases
GWAS			Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced) ( 24236485) Bipolar disorder ( 31043756) HDL cholesterol levels ( 32203549) Hematocrit ( 32888494) Hemoglobin ( 32888494) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Platelet distribution width ( 32888494) Red blood cell count ( 32888494) Serum uric acid levels ( 30993211) Urate levels ( 31985003 31578528 23263486) Urate levels in obese individuals ( 25811787) Waist circumference ( 28552196) Weight ( 28552196) Zinc levels ( 26025379)
Interacting Genes		2 interacting genes: MLH1 MTDH	6 interacting genes: ARNTL CREBBP DBP HNF4G MYB TET2
Entrez ID		8714	3131
HPRD ID		06826	00797
Ensembl ID		ENSG00000108846	ENSG00000108924
Uniprot IDs		O15438 Q86VN9	Q16534
PDB IDs
Enriched GO Terms of Interacting Partners?
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