SERPINB7 and FBXO22

Data Source:
BioGRID (affinity chromatography technology)

		SERPINB7	FBXO22
Description		serpin family B member 7	F-box protein 22
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm	Cytosol Z Disc
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity	Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Negative Regulation Of Endopeptidase Activity Positive Regulation Of Transforming Growth Factor Beta1 Production Positive Regulation Of Collagen Biosynthetic Process Positive Regulation Of Glomerular Mesangial Cell Proliferation Positive Regulation Of Platelet-derived Growth Factor Production	Protein Polyubiquitination Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Regulation Of Skeletal Muscle Fiber Development
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Asthma ( 31361310 30929738 32296059 31619474) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433 30929738) Asthma onset (childhood vs adult) ( 30929738) Food allergy ( 29051540) Hen's egg allergy ( 29051540) Systolic blood pressure ( 29208002)	Creatinine levels ( 29403010) Urate levels in obese individuals ( 25811787)
Interacting Genes			1 interacting genes: SNAI1
Entrez ID		8710	26263
HPRD ID		04524	16437
Ensembl ID		ENSG00000166396	ENSG00000167196
Uniprot IDs		A8K3Q8 O75635	Q8NEZ5
PDB IDs
Enriched GO Terms of Interacting Partners?
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