LGR5 and REEP5

Data Source:
HPRD (in vivo)

		LGR5	REEP5
Description		leucine rich repeat containing G protein-coupled receptor 5	receptor accessory protein 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Trans-Golgi Network Membrane	Endoplasmic Reticulum Integral Component Of Membrane Endoplasmic Reticulum Tubular Network
	Molecular Function	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Protein-hormone Receptor Activity	Molecular_function Protein Binding
	Biological Process	Hair Follicle Development G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Hormone-mediated Signaling Pathway Oocyte Differentiation Regulation Of Cell Population Proliferation Inner Ear Development Positive Regulation Of Canonical Wnt Signaling Pathway Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis	Endoplasmic Reticulum Organization Biological_process Regulation Of Intracellular Transport
Pathways		Regulation of FZD by ubiquitination	Olfactory Signaling Pathway
Drugs
Diseases
GWAS		Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Type 2 diabetes ( 22885922 18372903 29358691 30297969 32499647 20581827)	Attention deficit hyperactivity disorder ( 18839057) Reaction time ( 29844566)
Interacting Genes		1 interacting genes: RSPO2	13 interacting genes: ABHD4 ARFGAP1 ARFIP2 CHRM5 GTF2H1 NUDT3 PBX3 PITPNC1 RAB5B RABAC1 RGS2 SNX1 VKORC1
Entrez ID		8549	7905
HPRD ID		05979	15918
Ensembl ID		ENSG00000139292	ENSG00000129625
Uniprot IDs		A0A0A8K8C7 O75473	Q00765
PDB IDs		4BSR 4BSS 4BST 4BSU 4KNG 4UFR 4UFS
Enriched GO Terms of Interacting Partners?
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