AP3B1 and ZER1

Data Source:
BioGRID (affinity chromatography technology)

		AP3B1	ZER1
Description		adaptor related protein complex 3 subunit beta 1	zyg-11 related cell cycle regulator
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Lysosomal Membrane Golgi Apparatus Membrane AP-3 Adaptor Complex Clathrin Adaptor Complex Clathrin-coated Vesicle Membrane Synapse Axon Cytoplasm	Cul2-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Protein Phosphatase Binding GTP-dependent Protein Binding
	Biological Process	Cell Morphogenesis Toll-like Receptor Signaling Pathway Hematopoietic Progenitor Cell Differentiation Respiratory System Process Cellular Protein Modification Process Protein Targeting To Lysosome Cellular Zinc Ion Homeostasis Intracellular Protein Transport Inflammatory Response Lysosome Organization Spermatogenesis Single Fertilization Blood Coagulation Anterograde Axonal Transport Synaptic Vesicle Budding From Endosome Vesicle-mediated Transport Granulocyte Differentiation Melanosome Organization Protein Localization To Cell Surface MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Anterograde Synaptic Vesicle Transport Homeostasis Of Number Of Cells Regulation Of Catalytic Activity Positive Regulation Of NK T Cell Differentiation Platelet Dense Granule Organization Lung Morphogenesis Establishment Of Protein Localization To Mitochondrial Membrane Involved In Mitochondrial Fission Skin Epidermis Development	Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Pathways		Golgi Associated Vesicle Biogenesis Signaling by BRAF and RAF fusions
Drugs
Diseases		Hermansky-Pudlak syndrome (HPS)
GWAS		Adult body size ( 32376654) Body size at age 10 ( 32376654) Cardiovascular death, myocardial infarction or stroke in response to clopidogrel treatment ( 32472697) FEV1 ( 30804560) Insulin resistance/response ( 21901158) Lung function (FEV1) ( 30061609) Lung function (FVC) ( 30061609 30804560) Metabolite levels ( 23823483) Red cell distribution width ( 32888494) Triglycerides ( 26780889) Type 2 diabetes ( 31049640)	Axial length ( 24144296) Body mass index ( 26426971) Eating disorders (purging via substances) ( 23568457) LDL cholesterol levels ( 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes		14 interacting genes: AP3D1 AP3S2 ARF1 ARF5 ARF6 ARR3 ATM ATR BUB1 BUB1B CLTC CSNK1A1 GKAP1 SLC30A3	2 interacting genes: CUL2 MLH1
Entrez ID		8546	10444
HPRD ID		04551	10802
Ensembl ID		ENSG00000132842	ENSG00000160445
Uniprot IDs		A0A0S2Z5J4 O00203	A0A024R8B0 Q7Z7L7
PDB IDs
Enriched GO Terms of Interacting Partners?
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