KCNAB2 and FAM3B

Data Source:
BioGRID (proximity labelling technology)

		KCNAB2	FAM3B
Description		potassium voltage-gated channel subfamily A regulatory beta subunit 2	FAM3 metabolism regulating signaling molecule B
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Microtubule Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Specific Granule Membrane Juxtaparanode Region Of Axon Synapse Tertiary Granule Membrane Pinceau Fiber	Extracellular Region Extracellular Space Extracellular Exosome
	Molecular Function	Aldo-keto Reductase (NADP) Activity Voltage-gated Potassium Channel Activity Protein Binding Potassium Channel Regulator Activity Ion Channel Binding	Cytokine Activity Protein Binding
	Biological Process	Neutrophil Degranulation NADPH Oxidation Potassium Ion Transmembrane Transport Regulation Of Action Potential Regulation Of Potassium Ion Transmembrane Transport Regulation Of Protein Localization To Cell Surface	Apoptotic Process Signal Transduction Insulin Secretion Glucose Homeostasis
Pathways		Voltage gated Potassium channels Neutrophil degranulation
Drugs		Enflurane Promethazine Miconazole
Diseases
GWAS		Metabolite levels ( 23823483)	Blood protein levels ( 30072576 29875488) Elevated serum carcinoembryonic antigen levels ( 24941225) Glycemic traits (pregnancy) ( 23903356) Tumor biomarkers ( 23300138)
Interacting Genes		8 interacting genes: ATXN1 CD4 KCNA2 NEDD4 NEDD4L SLC39A1 SLC39A2 SQSTM1	2 interacting genes: APP FUT3
Entrez ID		8514	54097
HPRD ID		03090	10552
Ensembl ID		ENSG00000069424	ENSG00000183844
Uniprot IDs		A1PR14 B2R776 Q13303	P58499
PDB IDs		1ZSX
Enriched GO Terms of Interacting Partners?
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