FRMD5 and SC5D

Data Source:
BioGRID (pull down)

		FRMD5	SC5D
Description		FERM domain containing 5	sterol-C5-desaturase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoskeleton Adherens Junction Integral Component Of Membrane	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Integrin Binding Protein Binding Cytoskeletal Protein Binding Protein Kinase Binding	C-5 Sterol Desaturase Activity Iron Ion Binding Oxidoreductase Activity
	Biological Process	Regulation Of Cell Migration Actomyosin Structure Organization Positive Regulation Of Cell Adhesion Negative Regulation Of Cell Motility	Lipid Metabolic Process Sterol Biosynthetic Process Cholesterol Biosynthetic Process Via Desmosterol Cholesterol Biosynthetic Process Via Lathosterol Regulation Of Cholesterol Biosynthetic Process
Pathways			Activation of gene expression by SREBF (SREBP) Cholesterol biosynthesis via desmosterol Cholesterol biosynthesis via lathosterol
Drugs
Diseases
GWAS		Hemoglobin levels ( 32327693) Lipoprotein phospholipase A2 activity in cardiovascular disease ( 28753643) Serum albumin level ( 23022100) Triglyceride levels ( 28334899) Triglycerides ( 24097068 25961943 20686565) Urinary tract infection frequency ( 28928442) Uterine fibroid number (single vs multiple) ( 30196971)
Interacting Genes		1 interacting genes: NELFCD
Entrez ID		84978	6309
HPRD ID		17493	09078
Ensembl ID		ENSG00000171877	ENSG00000109929
Uniprot IDs		A0A087WVP2 B3KVN9 B5MC67 H0YKW6 Q7Z6J6	A0A024R3G4 O75845
PDB IDs
Enriched GO Terms of Interacting Partners?
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