FBXL20 and PPP1R1B

Data Source:
BioGRID (affinity chromatography technology)

		FBXL20	PPP1R1B
Description		F-box and leucine rich repeat protein 20	protein phosphatase 1 regulatory inhibitor subunit 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol SCF Ubiquitin Ligase Complex	Nucleus Cytoplasm Cytosol Neuronal Cell Body Dendritic Spine Neck Dendritic Spine Head Glutamatergic Synapse
	Molecular Function	Protein Binding	Protein Kinase Inhibitor Activity Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase Regulator Activity D1 Dopamine Receptor Binding D2 Dopamine Receptor Binding D3 Dopamine Receptor Binding D4 Dopamine Receptor Binding D5 Dopamine Receptor Binding
	Biological Process	Protein Polyubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification	Response To Amphetamine Transcription, DNA-templated Negative Regulation Of Protein Kinase Activity Signal Transduction Memory Negative Regulation Of Female Receptivity Locomotory Behavior Visual Learning Negative Regulation Of Phosphoprotein Phosphatase Activity Response To Nicotine Intracellular Signal Transduction Response To Morphine Behavioral Response To Cocaine
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	DARPP-32 events DARPP-32 events
Drugs
Diseases
GWAS		Asthma ( 31619474) Coronary artery disease ( 29212778) Creatinine levels ( 31015462) Estimated glomerular filtration rate in non-diabetics ( 31451708) FEV1 ( 30804560) Glomerular filtration rate (creatinine) ( 26831199) Hemoglobin levels ( 32327693) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Lung function (FVC) ( 30804560) Mean platelet volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Microalbuminuria ( 31511532) Platelet count ( 32888494) Rapid automised naming of pictures ( 30741946) Red cell distribution width ( 32888494) Refractive error ( 32231278) Ulcerative colitis ( 20228799) Urinary albumin excretion ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532)	Asthma ( 31959851 31619474) Estimated glomerular filtration rate ( 31015462) Hematocrit ( 32888494) Hemoglobin ( 32888494) Refractive error ( 32231278) Ulcerative colitis ( 20228799)
Interacting Genes		2 interacting genes: PIK3C3 SKP1	9 interacting genes: CDK5 CSNK2A1 CSNK2A2 DLGAP4 KLHL6 PPP1CA PRKACA ROBO2 TFCP2
Entrez ID		84961	84152
HPRD ID		10951	05097
Ensembl ID		ENSG00000108306	ENSG00000131771
Uniprot IDs		Q96IG2	A0A024R1R3 B3KVQ9 Q9UD71
PDB IDs
Enriched GO Terms of Interacting Partners?
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