PHF5A and CENPM

Data Source:
HPRD (in vitro, in vivo)

		PHF5A	CENPM
Description		PHD finger protein 5A	centromere protein M
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GO Annotations	Cellular Component	Nucleus Nucleoplasm U2 SnRNP U12-type Spliceosomal Complex Nuclear Matrix Nuclear Speck U2-type Precatalytic Spliceosome Precatalytic Spliceosome	Condensed Chromosome Kinetochore Nucleoplasm Cytosol
	Molecular Function	DNA Binding RNA Binding Protein Binding Zinc Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome Positive Regulation Of Transcription, DNA-templated Stem Cell Differentiation	CENP-A Containing Nucleosome Assembly
Pathways		mRNA Splicing - Major Pathway	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Asthma ( 30929738 32296059) Asthma (childhood onset) ( 30929738) Chronotype ( 30696823) Experiencing mood swings ( 29500382) Feeling tense ( 29500382) Lamb consumption ( 32066663) Meat-related diet ( 32066663) Neuroticism ( 29255261) PR interval ( 32439900) Refractive error ( 32231278)	Birth weight ( 23202124) Processed meat consumption ( 32066663) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		8 interacting genes: FOXB1 PRPF31 SF3B1 SF3B3 SF3B6 SUMO2 U2AF2 ZDHHC17	2 interacting genes: CENPS H3C1
Entrez ID		84844	79019
HPRD ID		15126	12798
Ensembl ID		ENSG00000100410	ENSG00000100162
Uniprot IDs		A0A024R1U2 Q7RTV0	A0A024R1Q3 B1AHQ6 B1AHQ7 B1AHQ8 Q9NSP4
PDB IDs		5IFE 5O9Z 5SYB 5Z56 5Z57 5Z58 5ZYA 6AH0 6EN4 6FF4 6FF7 6QX9 6Y50 6Y5Q	4P0T 4WAU
Enriched GO Terms of Interacting Partners?
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