GPR65 and TRIP11

Data Source:
BioGRID (biochemical)

		GPR65	TRIP11
Description		G protein-coupled receptor 65	thyroid hormone receptor interactor 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Golgi Membrane Inner Acrosomal Membrane Outer Acrosomal Membrane Nucleoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Cytoskeleton Cilium Nuclear Speck Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	G Protein-coupled Receptor Activity	Transcription Coactivator Activity Protein Binding Small GTPase Binding
	Biological Process	Apoptotic Process Immune Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Multicellular Organism Development Response To Acidic PH Actin Cytoskeleton Reorganization Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Positive Regulation Of Stress Fiber Assembly Activation Of GTPase Activity	Ventricular Septum Development Chondrocyte Differentiation Involved In Endochondral Bone Morphogenesis Transcription By RNA Polymerase II Protein Glycosylation Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Intraciliary Transport Involved In Cilium Assembly Positive Regulation Of Transcription, DNA-templated Cartilage Development Inner Ear Receptor Cell Stereocilium Organization Golgi Ribbon Formation Vesicle Tethering To Golgi
Pathways		Class A/1 (Rhodopsin-like receptors) G alpha (q) signalling events	Intraflagellar transport Intra-Golgi traffic Signaling by FLT3 fusion proteins Signaling by FLT3 fusion proteins
Drugs
Diseases			Achodrogenesis type IA
GWAS		Ankylosing spondylitis ( 23749187) California verbal learning test score ( 31596458) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Crohn's disease ( 28067908 21102463) Degraded stimulus continuous performance test score ( 31596458) Diastolic blood pressure night-to-day ratio in hypertension ( 29973135) Eosinophil percentage of white cells ( 32888494) Food antigen IgG levels ( 24962563) Inflammatory bowel disease ( 28067908 23128233) Multiple sclerosis ( 21833088) Parkinson's disease ( 32201043) Takayasu arteritis ( 25604533)	Body size at age 10 ( 32376654) FEV1 ( 30804560) HDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Height ( 28552196 20881960 25282103 25429064 31562340 18391950 18391951) LDL cholesterol levels x loop diuretics use interaction ( 31806883) Lung function (FEV1) ( 26635082) Lung function (FVC) ( 26635082 30804560) Refractive error ( 32231278) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 25673412 28448500)
Interacting Genes			6 interacting genes: ARNT ATXN1L MYBPC2 PSMC5 RB1 THRA
Entrez ID		8477	9321
HPRD ID		07057	05143
Ensembl ID		ENSG00000140030	ENSG00000100815
Uniprot IDs		B5B0C2 Q8IYL9	Q15643
PDB IDs
Enriched GO Terms of Interacting Partners?
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