PPP1R1B and FBXL20

Data Source:
BioGRID (affinity chromatography technology)

		PPP1R1B	FBXL20
Description		protein phosphatase 1 regulatory inhibitor subunit 1B	F-box and leucine rich repeat protein 20
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Neuronal Cell Body Dendritic Spine Neck Dendritic Spine Head Glutamatergic Synapse	Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	Protein Kinase Inhibitor Activity Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase Regulator Activity D1 Dopamine Receptor Binding D2 Dopamine Receptor Binding D3 Dopamine Receptor Binding D4 Dopamine Receptor Binding D5 Dopamine Receptor Binding	Protein Binding
	Biological Process	Response To Amphetamine Transcription, DNA-templated Negative Regulation Of Protein Kinase Activity Signal Transduction Memory Negative Regulation Of Female Receptivity Locomotory Behavior Visual Learning Negative Regulation Of Phosphoprotein Phosphatase Activity Response To Nicotine Intracellular Signal Transduction Response To Morphine Behavioral Response To Cocaine	Protein Polyubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification
Pathways		DARPP-32 events DARPP-32 events	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Asthma ( 31959851 31619474) Estimated glomerular filtration rate ( 31015462) Hematocrit ( 32888494) Hemoglobin ( 32888494) Refractive error ( 32231278) Ulcerative colitis ( 20228799)	Asthma ( 31619474) Coronary artery disease ( 29212778) Creatinine levels ( 31015462) Estimated glomerular filtration rate in non-diabetics ( 31451708) FEV1 ( 30804560) Glomerular filtration rate (creatinine) ( 26831199) Hemoglobin levels ( 32327693) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Lung function (FVC) ( 30804560) Mean platelet volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Microalbuminuria ( 31511532) Platelet count ( 32888494) Rapid automised naming of pictures ( 30741946) Red cell distribution width ( 32888494) Refractive error ( 32231278) Ulcerative colitis ( 20228799) Urinary albumin excretion ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532)
Interacting Genes		9 interacting genes: CDK5 CSNK2A1 CSNK2A2 DLGAP4 KLHL6 PPP1CA PRKACA ROBO2 TFCP2	2 interacting genes: PIK3C3 SKP1
Entrez ID		84152	84961
HPRD ID		05097	10951
Ensembl ID		ENSG00000131771	ENSG00000108306
Uniprot IDs		A0A024R1R3 B3KVQ9 Q9UD71	Q96IG2
PDB IDs
Enriched GO Terms of Interacting Partners?
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