ACAD11 and NEK11

Data Source:
BioGRID (two hybrid)

		ACAD11	NEK11
Description		acyl-CoA dehydrogenase family member 11	NIMA related kinase 11
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Inner Membrane Peroxisome Mitochondrial Membrane	Nucleus Nucleoplasm Nucleolus Cytoplasm Centrosome
	Molecular Function	Acyl-CoA Dehydrogenase Activity Long-chain-acyl-CoA Dehydrogenase Activity Protein Binding Very-long-chain-acyl-CoA Dehydrogenase Activity Flavin Adenine Dinucleotide Binding Medium-chain-acyl-CoA Dehydrogenase Activity	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Fatty Acid Beta-oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Dehydrogenase	Protein Phosphorylation Chromosome Segregation Histone Phosphorylation Intra-S DNA Damage Checkpoint Intracellular Signal Transduction Regulation Of Mitotic Cell Cycle Phase Transition
Pathways		Mitochondrial Fatty Acid Beta-Oxidation
Drugs			Dabrafenib Fostamatinib
Diseases
GWAS		Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) HDL cholesterol ( 24097068) HDL cholesterol levels ( 28334899) Hemoglobin levels ( 32327693) LDL cholesterol ( 24097068) LDL cholesterol levels ( 28334899) Menarche (age at onset) ( 25231870) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)	Carotid intima media thickness ( 26343869) Hip bone mineral density and total body fat mass (bivariate analysis) ( 32963334) Hippocampal sclerosis ( 25188341) Phenylephrine infusion rate during anesthesia ( 31455332) Weight ( 28552196)
Interacting Genes		2 interacting genes: APP CD2BP2	5 interacting genes: APP BLM MFHAS1 MYC NEK2
Entrez ID		84129	79858
HPRD ID		13352	14821
Ensembl ID		ENSG00000240303	ENSG00000114670
Uniprot IDs		Q709F0	B4DDN2 B4DM56 E9PHI8 Q8NG66
PDB IDs		2WBI
Enriched GO Terms of Interacting Partners?
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