QRFPR and BBS7

Data Source:
BioGRID (affinity chromatography technology)

		QRFPR	BBS7
Description		pyroglutamylated RFamide peptide receptor	Bardet-Biedl syndrome 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Photoreceptor Outer Segment Nucleus Centrosome Cytosol Axoneme Membrane BBSome Ciliary Basal Body Neuron Projection Ciliary Membrane
	Molecular Function	G Protein-coupled Receptor Activity Neuropeptide Y Receptor Activity Protein Binding	RNA Polymerase II Repressing Transcription Factor Binding Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway	Eye Development Heart Looping Regulation Of Transcription By RNA Polymerase II Smoothened Signaling Pathway Determination Of Left/right Symmetry Brain Development Visual Perception Protein Localization Protein Transport Melanosome Transport Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Fat Cell Differentiation Intracellular Transport Digestive Tract Morphogenesis Pigment Granule Aggregation In Cell Center Limb Development Cilium Assembly Primary Palate Development Non-motile Cilium Assembly
Pathways		Orexin and neuropeptides FF and QRFP bind to their respective receptors G alpha (q) signalling events	BBSome-mediated cargo-targeting to cilium
Drugs
Diseases			Bardet-Biedl syndrome (BBS)
GWAS			Asthma ( 31959851)
Interacting Genes		2 interacting genes: GJA8 NTM	4 interacting genes: FHOD1 JUN KRT18 PAX2
Entrez ID		84109	55212
HPRD ID		09494	07399
Ensembl ID		ENSG00000186867	ENSG00000138686
Uniprot IDs		F2Z3L3 Q96P65	Q8IWZ6
PDB IDs
Enriched GO Terms of Interacting Partners?
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