LMAN2L and TMEM127

Data Source:
BioGRID (affinity chromatography technology)

		LMAN2L	TMEM127
Description		lectin, mannose binding 2 like	transmembrane protein 127
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Integral Component Of Membrane COPII-coated ER To Golgi Transport Vesicle	Cytoplasm Early Endosome Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Mannose Binding Metal Ion Binding	Molecular_function Small GTPase Binding
	Biological Process	Protein Folding Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Organization Golgi Organization Protein Transport	Endosome Organization Negative Regulation Of Cell Population Proliferation Regulation Of TOR Signaling Negative Regulation Of TOR Signaling
Pathways		COPII-mediated vesicle transport Cargo concentration in the ER
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 22182935 21926972 31043756 28072414 20351715) Blood protein levels ( 30072576 29875488)	Type 2 diabetes (adjusted for BMI) ( 30297969)
Interacting Genes		2 interacting genes: MAL ZDHHC17
Entrez ID		81562	55654
HPRD ID		17286	07917
Ensembl ID		ENSG00000114988	ENSG00000135956
Uniprot IDs		B4DI83 B4DVH1 B4E308 Q9H0V9	C9J4H2 O75204 Q9H6I0
PDB IDs
Enriched GO Terms of Interacting Partners?
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