FXR1 and MRPL19

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)

		FXR1	MRPL19
Description		FMR1 autosomal homolog 1	mitochondrial ribosomal protein L19
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GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Cytosol Polysome Postsynaptic Density Membrane Axon Growth Cone Cytoplasmic Ribonucleoprotein Granule Neuronal Cell Body Costamere Dendritic Spine Dendritic Spine Neck Perinuclear Region Of Cytoplasm Presynapse Glutamatergic Synapse Dendritic Filopodium	Nucleus Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit Nuclear Membrane
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Protein Binding RNA Strand Annealing Activity Protein Homodimerization Activity Translation Regulator Activity Protein Heterodimerization Activity	Structural Constituent Of Ribosome Protein Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Protein Phosphorylation Apoptotic Process Muscle Organ Development Negative Regulation Of Translation Cell Differentiation Regulation Of MRNA Stability Positive Regulation Of Translation Regulation Of Filopodium Assembly Skeletal Muscle Organ Development Positive Regulation Of Gene Silencing By MiRNA Positive Regulation Of Response To DNA Damage Stimulus	Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways		Signaling by BRAF and RAF fusions	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases
GWAS		Bipolar disorder and eating disorder ( 26433762) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Eating disorder in bipolar disorder ( 26433762) Metabolite levels ( 23823483) Schizophrenia ( 25056061 19571811 29483656 30285260)	Diabetic macular edema in type 2 diabetes ( 29739359) Metabolite levels ( 23823483)
Interacting Genes		48 interacting genes: AP1M1 BLK BYSL C1orf35 CBX8 CCDC187 CDC7 CDKL3 CEP126 CRMP1 CSNK2A1 CWF19L2 CYFIP2 DHX15 ELOA ERCC6 ERG28 ESCO2 FAM161A FAM90A1 FBXO4 FMR1 FXR2 GBP2 HSPB1 KIF9 LNX1 LRIF1 LUC7L2 MAGOH MAGOHB MCRS1 MFAP1 PRAM1 PRPF31 PRSS23 SRPK2 STK16 SUFU SYT6 TBC1D22B TCEA2 TRPM1 YES1 ZMAT2 ZNF417 ZNF438 ZNF71	7 interacting genes: APP LRRK2 MAGEC1 NEDD4 NEDD4L TRIM55 TRIM63
Entrez ID		8087	9801
HPRD ID		02892	11370
Ensembl ID		ENSG00000114416	ENSG00000115364
Uniprot IDs		A0A0F7KYT8 A0A0F7L1S3 P51114	P49406
PDB IDs		2CPQ 3KUF 3O8V	3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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