SCUBE1 and PRR5

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		SCUBE1	PRR5
Description		signal peptide, CUB domain and EGF like domain containing 1	proline rich 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane External Side Of Plasma Membrane Cell Surface Extrinsic Component Of Plasma Membrane	Cytosol TORC2 Complex
	Molecular Function	Calcium Ion Binding Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Inflammatory Response Signal Transduction Adult Heart Development Blood Coagulation Post-embryonic Development Extracellular Matrix Disassembly Endothelial Cell Differentiation Positive Regulation Of Smoothened Signaling Pathway	Cell Cycle Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Activation Of Protein Kinase B Activity TORC2 Signaling
Pathways		Degradation of the extracellular matrix	PIP3 activates AKT signaling CD28 dependent PI3K/Akt signaling VEGFR2 mediated vascular permeability Constitutive Signaling by AKT1 E17K in Cancer Regulation of TP53 Degradation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Molar-incisor hypomineralization ( 23918034) Response to fenofibrate (adiponectin levels) ( 23149075) Sensory peripheral neuropathy in microtubule targeting agent-treated breast cancer ( 32562552) Waist circumference adjusted for body mass index ( 28552196)	Binge eating behaviour in bipolar disorder ( 24882193 29391396) Electroencephalographic traits in alcoholism ( 22554406)
Interacting Genes		2 interacting genes: SCUBE2 SCUBE3	5 interacting genes: CTNNA3 DESI1 GPSM3 HGS USHBP1
Entrez ID		80274	55615
HPRD ID		18029	18696
Ensembl ID		ENSG00000159307	ENSG00000186654
Uniprot IDs		A0JP65 Q6ZS56 Q86TI6 Q8IWY4	A0A024R4U5 A8K699 P85299
PDB IDs
Enriched GO Terms of Interacting Partners?
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