GRPEL1 and SFTPB

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)

		GRPEL1	SFTPB
Description		GrpE like 1, mitochondrial	surfactant protein B
Image		No pdb structure
GO Annotations	Cellular Component	PAM Complex, Tim23 Associated Import Motor Nucleoplasm Mitochondrion Mitochondrial Matrix	Extracellular Region Extracellular Space Nucleoplasm Lysosome Multivesicular Body Endoplasmic Reticulum Membrane Lamellar Body Clathrin-coated Endocytic Vesicle Alveolar Lamellar Body Multivesicular Body Lumen
	Molecular Function	Adenyl-nucleotide Exchange Factor Activity Protein Binding Identical Protein Binding Protein Homodimerization Activity Unfolded Protein Binding Chaperone Binding	Protein Binding
	Biological Process	Protein Folding Protein Import Into Mitochondrial Matrix Regulation Of Catalytic Activity	Sphingolipid Metabolic Process Respiratory Gaseous Exchange By Respiratory System Animal Organ Morphogenesis Cellular Protein Metabolic Process
Pathways		Mitochondrial protein import	Surfactant metabolism Defective pro-SFTPB causes SMDP1 and RDS Defective CSF2RB causes SMDP5 Defective CSF2RA causes SMDP4
Drugs
Diseases			Pulmonary surfactant metabolism dysfunction (SMDP)
GWAS		Eosinophil percentage of white cells ( 32888494)	Blood protein levels ( 30072576)
Interacting Genes		6 interacting genes: CCDC57 ERCC6 GALT POLR1C SPG21 WBP2	2 interacting genes: CTSH MEOX2
Entrez ID		80273	6439
HPRD ID		07550	01523
Ensembl ID		ENSG00000109519	ENSG00000168878
Uniprot IDs		Q9HAV7	D6W5L6 P07988
PDB IDs			1DFW 1KMR 1RG3 1RG4 1SSZ 2DWF 2JOU 2M0H 2M1T
Enriched GO Terms of Interacting Partners?
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