GRPEL1 and NKX3-2

Data Source:
BioGRID (genetic interference)

		GRPEL1	NKX3-2
Description		GrpE like 1, mitochondrial	NK3 homeobox 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	PAM Complex, Tim23 Associated Import Motor Nucleoplasm Mitochondrion Mitochondrial Matrix	Chromatin Nucleus
	Molecular Function	Adenyl-nucleotide Exchange Factor Activity Protein Binding Identical Protein Binding Protein Homodimerization Activity Unfolded Protein Binding Chaperone Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Protein Folding Protein Import Into Mitochondrial Matrix Regulation Of Catalytic Activity	Negative Regulation Of Transcription By RNA Polymerase II Skeletal System Development Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Determination Of Left/right Symmetry Cell Differentiation Pancreas Development Negative Regulation Of Chondrocyte Differentiation Middle Ear Morphogenesis Negative Regulation Of Apoptotic Process Spleen Development Animal Organ Formation Skeletal System Morphogenesis Embryonic Skeletal System Development Intestinal Epithelial Cell Development
Pathways		Mitochondrial protein import	Regulation of RUNX2 expression and activity
Drugs
Diseases			Spondylo-megaepiphyseal-metaphyseal dysplasia
GWAS		Eosinophil percentage of white cells ( 32888494)	Metabolite levels ( 23823483) Periodontal disease-related phenotype (Socransky) ( 24347629)
Interacting Genes		6 interacting genes: CCDC57 ERCC6 GALT POLR1C SPG21 WBP2	4 interacting genes: HDAC1 POU6F2 SMAD1 SMAD4
Entrez ID		80273	579
HPRD ID		07550	09075
Ensembl ID		ENSG00000109519	ENSG00000109705
Uniprot IDs		Q9HAV7	P78367
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?