FUZ and KLK7

Data Source:
BioGRID (affinity chromatography technology)

		FUZ	KLK7
Description		fuzzy planar cell polarity protein	kallikrein related peptidase 7
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Cell Projection Extracellular Exosome	Extracellular Region Extracellular Space Secretory Granule Epidermal Lamellar Body
	Molecular Function	Protein Binding	Serine-type Endopeptidase Activity Peptidase Activity Serine-type Peptidase Activity
	Biological Process	Establishment Of Planar Polarity Neural Tube Closure Hair Follicle Development Negative Regulation Of Cell Population Proliferation Regulation Of Smoothened Signaling Pathway Embryonic Body Morphogenesis Protein Transport Vesicle-mediated Transport Negative Regulation Of Cell Migration Positive Regulation Of Cilium Assembly Embryonic Skeletal System Morphogenesis Cilium Assembly Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Neural Crest Formation Non-motile Cilium Assembly Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation	Positive Regulation Of Antibacterial Peptide Production Proteolysis Epidermis Development Extracellular Matrix Disassembly
Pathways		Hedgehog 'off' state	Degradation of the extracellular matrix
Drugs			L-alanyl-N-[(1S,2R)-1-benzyl-2-hydroxypropyl]-L-alaninamide
Diseases
GWAS			Blood protein levels ( 30072576 29875488 28240269)
Interacting Genes		1 interacting genes: CPLANE2	10 interacting genes: APP BAG4 CCND1 CDSN CHEK2 PTPN1 PTPRJ STK11 TGFB1 WT1
Entrez ID		80199	5650
HPRD ID		08662	05115
Ensembl ID		ENSG00000010361	ENSG00000169035
Uniprot IDs		A0A024QZF7 Q9BT04	A0A024R4H6 B4DHX9 P49862
PDB IDs			2QXG 2QXH 2QXI 2QXJ 3BSQ 5FAH 5Y9L 5YJK 6SHH 6SHI 6SJU 6Y4S
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?