BICC1 and CISD1

Data Source:
BioGRID (affinity chromatography technology)

		BICC1	CISD1
Description		BicC family RNA binding protein 1	CDGSH iron sulfur domain 1
Image
GO Annotations	Cellular Component	Cytoplasm	Mitochondrion Mitochondrial Outer Membrane Integral Component Of Membrane Cytoplasmic Side Of Mitochondrial Outer Membrane
	Molecular Function	RNA Binding	Identical Protein Binding Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding
	Biological Process	Kidney Development Determination Of Left/right Symmetry Heart Development Negative Regulation Of Canonical Wnt Signaling Pathway	Regulation Of Cellular Respiration
Pathways
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 31152163 29403010) Chronotype ( 30696823) Glaucoma ( 31959993 30054594) Glaucoma (multi-trait analysis) ( 31959993) Glaucoma (primary open-angle) ( 29891935) Heel bone mineral density ( 30598549) Hematocrit ( 32888494) Hemoglobin ( 29403010 32888494) Hemoglobin levels ( 32327693) Intraocular pressure ( 31959993) LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Manganese levels ( 26025379) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Midgestational circulating levels of PCBs ( 28235828) Morning person ( 30696823) Myopia ( 27182965) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661) Pulse pressure ( 27841878) Pursuit maintenance gain ( 29064472) Refractive error ( 23396134 32231278) Serum uric acid levels ( 30993211 29403010) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Urate levels ( 31985003 31578528)	Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233)
Interacting Genes
Entrez ID		80114	55847
HPRD ID		18993	12587
Ensembl ID		ENSG00000122870	ENSG00000122873
Uniprot IDs		Q9H694	A0A024QZN7 Q9NZ45
PDB IDs		4RQM 4RQN 6GY4	2QD0 2QH7 2R13 3EW0 3LPQ 3REE 4EZF 4F1E 4F28 4F2C 6DE9
Enriched GO Terms of Interacting Partners?
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