KCTD17 and ARL8A

Data Source:
HPRD (in vitro)

		KCTD17	ARL8A
Description		potassium channel tetramerization domain containing 17	ADP ribosylation factor like GTPase 8A
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GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Cul3-RING Ubiquitin Ligase Complex	Cytoplasm Lysosomal Membrane Vacuolar Membrane Plasma Membrane Membrane Midbody Late Endosome Membrane Azurophil Granule Membrane Synapse Spindle Midzone Extracellular Exosome Ficolin-1-rich Granule Membrane Axon Cytoplasm
	Molecular Function	Protein Binding Identical Protein Binding Cullin Family Protein Binding	GTPase Activity Protein Binding GTP Binding Alpha-tubulin Binding Beta-tubulin Binding
	Biological Process	Cell Projection Organization Endoplasmic Reticulum Calcium Ion Homeostasis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cilium Assembly Protein Homooligomerization	Cell Cycle Chromosome Segregation Anterograde Axonal Transport Protein Transport Neutrophil Degranulation Cell Division
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		Iron status biomarkers (ferritin levels) ( 28334935) Mean corpuscular hemoglobin concentration ( 28453575) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet distribution width ( 32888494) Red blood cell traits ( 23222517)
Interacting Genes		24 interacting genes: AQP1 CRK CUL3 DMC1 FARS2 LAT LNX1 LRRC18 MGAT5B NCK2 NIF3L1 NUDT18 OR51E1 PLCG2 PSMA1 RBX1 RIN3 RWDD4 STK16 SUV39H2 TCHP TINF2 TUBGCP4 UBE2D1	4 interacting genes: MOCOS PUF60 SPG21 UQCRH
Entrez ID		79734	127829
HPRD ID		07764	09807
Ensembl ID		ENSG00000100379	ENSG00000143862
Uniprot IDs		A0A087WX35 Q8N5Z5	A0A024R977 A0A087X2J2 Q96BM9
PDB IDs		5A6R	1ZD9 2H18 4ILE
Enriched GO Terms of Interacting Partners?
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