CALB2 and NFATC3

Data Source:
BioGRID (pull down)

		CALB2	NFATC3
Description		calbindin 2	nuclear factor of activated T cells 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Gap Junction Dendrite Stereocilium Cuticular Plate Neuron Projection Terminal Bouton Synapse Synaptic Membrane Parallel Fiber To Purkinje Cell Synapse	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol
	Molecular Function	Calcium Ion Binding Calcium Ion Binding Involved In Regulation Of Presynaptic Cytosolic Calcium Ion Concentration	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Regulation Of Long-term Synaptic Potentiation	Cytokine Production Regulation Of Transcription By RNA Polymerase II Inflammatory Response Multicellular Organism Development Calcineurin-NFAT Signaling Cascade Fc-epsilon Receptor Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Pri-miRNA Transcription By RNA Polymerase II Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation
Pathways			Calcineurin activates NFAT Calcineurin activates NFAT FCERI mediated Ca+2 mobilization CLEC7A (Dectin-1) induces NFAT activation
Drugs		Calcium citrate Calcium Phosphate Calcium levulinate Calcium phosphate dihydrate
Diseases
GWAS		Body mass index ( 30271922) General risk tolerance (MTAG) ( 30643258) Mood instability ( 31168069) Risk-taking tendency (4-domain principal component model) ( 30643258) Self-reported risk-taking behaviour ( 30271922)	Chronotype ( 30696823) Estimated glomerular filtration rate ( 31015462) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Urate levels ( 31578528)
Interacting Genes		2 interacting genes: KRT1 TUBA4A	6 interacting genes: CDK6 CSNK1A1 FOS MAPK8 MAPK9 TTF1
Entrez ID		794	4775
HPRD ID		00230	04077
Ensembl ID		ENSG00000172137	ENSG00000072736
Uniprot IDs		A0A140VK08 A6NER6 P22676	B5B2S0 B5B2S1 Q12968
PDB IDs			2XRW 2XS0
Enriched GO Terms of Interacting Partners?
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