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DCTPP1 and SLX1B
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
DCTPP1
SLX1B
Description
dCTP pyrophosphatase 1
SLX1 homolog B, structure-specific endonuclease subunit
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Mitochondrion
Cytosol
Nucleoplasm
Slx1-Slx4 Complex
Molecular Function
Magnesium Ion Binding
Protein Binding
Pyrimidine Deoxyribonucleotide Binding
Identical Protein Binding
Nucleoside-triphosphate Diphosphatase Activity
DCTP Diphosphatase Activity
Protein Binding
Crossover Junction Endodeoxyribonuclease Activity
5'-flap Endonuclease Activity
Metal Ion Binding
Biological Process
DCTP Catabolic Process
Nucleoside Triphosphate Catabolic Process
DNA Protection
DTTP Catabolic Process
Double-strand Break Repair Via Homologous Recombination
DNA Repair
DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing
Telomere Maintenance Via Telomere Lengthening
Interstrand Cross-link Repair
Telomeric D-loop Disassembly
Nucleic Acid Phosphodiester Bond Hydrolysis
T-circle Formation
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
Positive Regulation Of T-circle Formation
Pathways
Interconversion of nucleotide di- and triphosphates
Resolution of D-loop Structures through Holliday Junction Intermediates
Fanconi Anemia Pathway
Drugs
Diseases
GWAS
Urinary sodium excretion (
31409800
)
Interacting Genes
9 interacting genes:
APP
LNX1
NIF3L1
NOA1
NTAQ1
PSMA1
SDCBP
SPG21
USP7
3 interacting genes:
DUSP10
THAP11
TUBA1B
Entrez ID
79077
79008
HPRD ID
18310
14673
Ensembl ID
ENSG00000179958
ENSG00000181625
Uniprot IDs
Q9H773
Q9BQ83
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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