REEP5 and EDC3

Data Source:
BioGRID (affinity chromatography technology)

		REEP5	EDC3
Description		receptor accessory protein 5	enhancer of mRNA decapping 3
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Integral Component Of Membrane Endoplasmic Reticulum Tubular Network	P-body Cytosol Membrane Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	Molecular_function Protein Binding	MRNA Binding Protein Binding Identical Protein Binding Phosphodiesterase Decapping Endonuclease Activity
	Biological Process	Endoplasmic Reticulum Organization Biological_process Regulation Of Intracellular Transport	Deadenylation-independent Decapping Of Nuclear-transcribed MRNA P-body Assembly Exonucleolytic Catabolism Of Deadenylated MRNA RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		Olfactory Signaling Pathway	mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 18839057) Reaction time ( 29844566)	Caffeine consumption ( 21490707) Caffeine metabolism (plasma 1,3,7-trimethylxanthine (caffeine) level) ( 27702941) Caffeine metabolism (plasma 1,3-dimethylxanthine (theophylline) level) ( 27702941) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941) Coffee consumption (cups per day) ( 31837886) Craniofacial microsomia ( 26853712) Mean platelet volume ( 32888494)
Interacting Genes		13 interacting genes: ABHD4 ARFGAP1 ARFIP2 CHRM5 GTF2H1 NUDT3 PBX3 PITPNC1 RAB5B RABAC1 RGS2 SNX1 VKORC1	11 interacting genes: ANXA10 DCP1B DDX6 EFHC2 LNX1 MIR15B PIAS2 QARS1 YWHAB YWHAG ZFP36
Entrez ID		7905	80153
HPRD ID		15918	07954
Ensembl ID		ENSG00000129625	ENSG00000179151
Uniprot IDs		Q00765	Q96F86
PDB IDs			2VC8 2WAX 2WAY 3D3J 3D3K 6S8S
Enriched GO Terms of Interacting Partners?
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