SLX1B and DCTPP1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SLX1B	DCTPP1
Description		SLX1 homolog B, structure-specific endonuclease subunit	dCTP pyrophosphatase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Slx1-Slx4 Complex	Nucleus Mitochondrion Cytosol
	Molecular Function	Protein Binding Crossover Junction Endodeoxyribonuclease Activity 5'-flap Endonuclease Activity Metal Ion Binding	Magnesium Ion Binding Protein Binding Pyrimidine Deoxyribonucleotide Binding Identical Protein Binding Nucleoside-triphosphate Diphosphatase Activity DCTP Diphosphatase Activity
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing Telomere Maintenance Via Telomere Lengthening Interstrand Cross-link Repair Telomeric D-loop Disassembly Nucleic Acid Phosphodiester Bond Hydrolysis T-circle Formation Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Positive Regulation Of T-circle Formation	DCTP Catabolic Process Nucleoside Triphosphate Catabolic Process DNA Protection DTTP Catabolic Process
Pathways		Resolution of D-loop Structures through Holliday Junction Intermediates Fanconi Anemia Pathway	Interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS			Urinary sodium excretion ( 31409800)
Interacting Genes		3 interacting genes: DUSP10 THAP11 TUBA1B	9 interacting genes: APP LNX1 NIF3L1 NOA1 NTAQ1 PSMA1 SDCBP SPG21 USP7
Entrez ID		79008	79077
HPRD ID		14673	18310
Ensembl ID		ENSG00000181625	ENSG00000179958
Uniprot IDs		Q9BQ83	Q9H773
PDB IDs
Enriched GO Terms of Interacting Partners?
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