VEGFB and UCP2

Data Source:
BioGRID (affinity chromatography technology)

		VEGFB	UCP2
Description		vascular endothelial growth factor B	uncoupling protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Membrane Platelet Alpha Granule Lumen	Mitochondrion Mitochondrial Inner Membrane Integral Component Of Membrane
	Molecular Function	Vascular Endothelial Growth Factor Receptor Binding Protein Binding Growth Factor Activity Heparin Binding Chemoattractant Activity Identical Protein Binding Vascular Endothelial Growth Factor Receptor 1 Binding	Protein Binding Oxidative Phosphorylation Uncoupler Activity
	Biological Process	Response To Hypoxia Positive Regulation Of Protein Phosphorylation Positive Regulation Of Endothelial Cell Proliferation Sprouting Angiogenesis Platelet Degranulation Protein O-linked Glycosylation Vascular Endothelial Growth Factor Signaling Pathway Response To Drug Positive Regulation Of Angiogenesis Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Chemotaxis Induction Of Positive Chemotaxis Positive Regulation Of Cell Division Cardiac Muscle Contraction Positive Regulation Of Mast Cell Chemotaxis Coronary Vasculature Development	Response To Superoxide Response To Hypoxia Female Pregnancy Aging Response To Cold Positive Regulation Of Cell Death Cellular Response To Insulin Stimulus Cellular Response To Amino Acid Starvation Negative Regulation Of Apoptotic Process Regulation Of Mitochondrial Membrane Potential Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Response To Fatty Acid Cellular Response To Glucose Stimulus Liver Regeneration Positive Regulation Of Cold-induced Thermogenesis Proton Transmembrane Transport Mitochondrial Transmembrane Transport Adaptive Thermogenesis
Pathways		Platelet degranulation VEGF ligand-receptor interactions VEGF binds to VEGFR leading to receptor dimerization	The fatty acid cycling model The proton buffering model
Drugs		Aflibercept
Diseases		Gastric cancer
GWAS		Apolipoprotein A1 levels ( 32203549) Crohn's disease ( 28067908) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Fruit consumption ( 32066663) HDL cholesterol levels ( 32203549) Red blood cell count ( 32888494) Triglyceride levels ( 32203549) Triglycerides ( 30275531) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for body mass index ( 25673412)	Mean platelet volume ( 32888494)
Interacting Genes		6 interacting genes: ADRB2 FLT1 KLHL12 NRP1 TNXB VEGFA	6 interacting genes: KRTAP10-3 KRTAP10-7 YWHAB YWHAG YWHAQ YWHAZ
Entrez ID		7423	7351
HPRD ID		03237	03410
Ensembl ID		ENSG00000173511	ENSG00000175567
Uniprot IDs		P49765 Q7LAP4	A0A024R5N5 P55851
PDB IDs		2C7W 2VWE 2XAC
Enriched GO Terms of Interacting Partners?
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