SHISA9 and BFAR

Data Source:
BioGRID (affinity chromatography technology)

		SHISA9	BFAR
Description		shisa family member 9	bifunctional apoptosis regulator
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ionotropic Glutamate Receptor Complex Postsynaptic Density AMPA Glutamate Receptor Complex Dendritic Spine Membrane Synapse Postsynaptic Membrane Glutamatergic Synapse Integral Component Of Postsynaptic Density Membrane	Endoplasmic Reticulum Integral Component Of Plasma Membrane Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	PDZ Domain Binding	Protein Binding Protein-macromolecule Adaptor Activity Metal Ion Binding Ubiquitin Protein Ligase Activity Caspase Binding
	Biological Process	Regulation Of Short-term Neuronal Synaptic Plasticity Regulation Of Postsynaptic Neurotransmitter Receptor Activity Regulation Of AMPA Receptor Activity	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Negative Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Negative Regulation Of IRE1-mediated Unfolded Protein Response
Pathways
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bone mineral density (total hip) ( 29883787) Cadmium levels ( 26025379) Copper levels ( 26025379) Depression ( 29700475) Height ( 31562340) Self-rated health ( 27864402) SjÃ¶gren's syndrome ( 28076899) Social science traits (pleiotropy) (HIPO component 1) ( 30289880) Triglyceride levels ( 31170924)
Interacting Genes			12 interacting genes: BCL2 CASP10 CASP8 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2K UBE2N UBE2U UBE2W
Entrez ID		729993	51283
HPRD ID		19683	16548
Ensembl ID		ENSG00000237515	ENSG00000103429
Uniprot IDs		B4DS77	H3BMP2 Q9NZS9
PDB IDs
Enriched GO Terms of Interacting Partners?
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