TSN and CFC1

Data Source:
BioGRID (proximity labelling technology)

		TSN	CFC1
Description		translin	cripto, FRL-1, cryptic family 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol	Cellular_component Extracellular Region Plasma Membrane Cell Surface Anchored Component Of Membrane
	Molecular Function	DNA Binding Single-stranded DNA Binding RNA Binding Endoribonuclease Activity Protein Binding Identical Protein Binding Sequence-specific DNA Binding Protein-containing Complex Binding	Molecular_function Signaling Receptor Binding Nodal Binding Activin Receptor Binding
	Biological Process	DNA Recombination Production Of SiRNA Involved In RNA Interference RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Blood Vessel Development Determination Of Left/right Symmetry Gastrulation Heart Development Anterior/posterior Pattern Specification Nodal Signaling Pathway Anatomical Structure Development
Pathways		Small interfering RNA (siRNA) biogenesis	Signaling by NODAL Regulation of signaling by NODAL
Drugs
Diseases			Conotruncal heart malformations, including: Double-outlet right ventricle; Persistent truncus arteriosus; Conotruncal anomaly face syndrome Heterotaxy; Situs ambiguus
GWAS		Diastolic blood pressure ( 27841878) Disease progression in age-related macular degeneration ( 29346644) Erectile dysfunction and prostate cancer treatment ( 20932654) Food antigen IgG levels ( 24962563) Hepcidin/ferritin ratio ( 27846281) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		13 interacting genes: DVL3 GIT2 GORASP2 LNX1 MORF4L2 NTAQ1 PICK1 PPP1R15A SDCBP TSNAX UBE2I UBE2K ZBTB18
Entrez ID		7247	55997
HPRD ID		08993	05548
Ensembl ID		ENSG00000211460	ENSG00000136698
Uniprot IDs		B3KRM8 Q15631	A0A087WWV2 A0A087WX98 P0CG37
PDB IDs		1J1J 3PJA 3QB5 4WYV
Enriched GO Terms of Interacting Partners?
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