HSP90B1 and EPB41L4B

Data Source:
HPRD (two hybrid, in vivo)

		HSP90B1	EPB41L4B
Description		heat shock protein 90 beta family member 1	erythrocyte membrane protein band 4.1 like 4B
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Cytosol Focal Adhesion Membrane Midbody Protein-containing Complex Sarcoplasmic Reticulum Lumen Melanosome Perinuclear Region Of Cytoplasm Collagen-containing Extracellular Matrix Extracellular Exosome Endocytic Vesicle Lumen	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Bicellular Tight Junction Apical Part Of Cell
	Molecular Function	RNA Binding Calcium Ion Binding Protein Binding ATP Binding Protein Phosphatase Binding Low-density Lipoprotein Particle Receptor Binding Unfolded Protein Binding	Structural Constituent Of Cytoskeleton Cytoskeletal Protein Binding
	Biological Process	Response To Hypoxia Toll-like Receptor Signaling Pathway Protein Folding Receptor-mediated Endocytosis Protein Transport Cytokine-mediated Signaling Pathway Ubiquitin-dependent ERAD Pathway Retrograde Protein Transport, ER To Cytosol Actin Rod Assembly Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress ATF6-mediated Unfolded Protein Response Negative Regulation Of Apoptotic Process Regulation Of Phosphoprotein Phosphatase Activity Post-translational Protein Modification Cellular Protein Metabolic Process Sequestering Of Calcium Ion Cellular Response To ATP	Positive Regulation Of Gene Expression Regulation Of Keratinocyte Proliferation Actomyosin Structure Organization Wound Healing Positive Regulation Of Cell Adhesion Positive Regulation Of Keratinocyte Migration
Pathways		Trafficking and processing of endosomal TLR Scavenging by Class A Receptors Scavenging by Class A Receptors ATF6 (ATF6-alpha) activates chaperone genes Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Interleukin-4 and Interleukin-13 signaling Post-translational protein phosphorylation
Drugs		Rifabutin 2-Chlorodideoxyadenosine Geldanamycin Diglyme N-Ethyl-5'-Carboxamido Adenosine Radicicol METHYL 3-CHLORO-2-{3-[(2,5-DIHYDROXY-4-METHOXYPHENYL)AMINO]-3-OXOPROPYL}-4,6-DIHYDROXYBENZOATE 2-(3-AMINO-2,5,6-TRIMETHOXYPHENYL)ETHYL 5-CHLORO-2,4-DIHYDROXYBENZOATE Copper
Diseases
GWAS		Blood protein levels ( 29875488) Metabolite levels ( 23823483) Soluble VCAM-1 levels ( 31217265)	Adult body size ( 32376654) Body mass index ( 28892062 25673413) Degraded stimulus continuous performance test score ( 31596458) Low vWF levels ( 26486471) Staphylococcus aureus nasal carriage (persistent) ( 26569114) Umami taste perception in obesity with metabolic syndrome ( 31005965)
Interacting Genes		36 interacting genes: APOB ASGR1 BIRC2 CACYBP CAMLG CCT2 CSNK2A1 CSNK2A2 CYSLTR2 EGFR ERBB2 ESR1 FANCC GPR37 HSPA9 LINC01554 LRP1 MAPK6 MDM2 MTTP NKX3-1 OS9 POLR2E PTEN PTPN11 RXFP3 SGTB SIRPA SUPT6H TG TLR1 TLR2 TLR4 TP53 TXNDC11 UBASH3A	2 interacting genes: LAMC3 SRPK2
Entrez ID		7184	54566
HPRD ID		01860	09940
Ensembl ID		ENSG00000166598	ENSG00000095203
Uniprot IDs		P14625 V9HWP2	Q59GC2 Q9H329 Q9NSG9 Q9NX84
PDB IDs		4NH9
Enriched GO Terms of Interacting Partners?
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