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TBX1 and MORC3
Data Source:
BioGRID
(unspecified method)
TBX1
MORC3
Description
T-box transcription factor 1
MORC family CW-type zinc finger 3
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Nuclear Matrix
PML Body
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Protein Homodimerization Activity
Sequence-specific DNA Binding
Sequence-specific Double-stranded DNA Binding
RNA Binding
Protein Binding
Zinc Ion Binding
Methylated Histone Binding
Biological Process
Angiogenesis
Blood Vessel Development
Cell Fate Specification
Neural Crest Cell Migration
Positive Regulation Of Protein Phosphorylation
Lymph Vessel Development
Positive Regulation Of Mesenchymal Cell Proliferation
Heart Morphogenesis
Outflow Tract Septum Morphogenesis
Outflow Tract Morphogenesis
Regulation Of Transcription By RNA Polymerase II
Determination Of Left/right Symmetry
Pattern Specification Process
Mesoderm Development
Heart Development
Muscle Organ Development
Sensory Perception Of Sound
Cell Population Proliferation
Positive Regulation Of Cell Population Proliferation
Anterior/posterior Pattern Specification
Vagus Nerve Morphogenesis
Epithelial Cell Differentiation
Thyroid Gland Development
Social Behavior
Aorta Morphogenesis
Ear Morphogenesis
Inner Ear Morphogenesis
Outer Ear Morphogenesis
Middle Ear Morphogenesis
Odontogenesis Of Dentin-containing Tooth
Muscle Cell Fate Commitment
Positive Regulation Of MAPK Cascade
Tongue Morphogenesis
Cellular Response To Fibroblast Growth Factor Stimulus
Negative Regulation Of Cell Differentiation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Retinoic Acid Receptor Signaling Pathway
Blood Vessel Morphogenesis
Thymus Development
Muscle Organ Morphogenesis
Embryonic Cranial Skeleton Morphogenesis
Embryonic Viscerocranium Morphogenesis
Semicircular Canal Morphogenesis
Artery Morphogenesis
Positive Regulation Of Epithelial Cell Proliferation
Parathyroid Gland Development
Soft Palate Development
Pharyngeal System Development
Face Morphogenesis
Muscle Tissue Morphogenesis
Coronary Artery Morphogenesis
Enamel Mineralization
Cellular Response To Retinoic Acid
Cochlea Morphogenesis
Mesenchymal Cell Apoptotic Process
Regulation Of Animal Organ Morphogenesis
Positive Regulation Of Tongue Muscle Cell Differentiation
Negative Regulation Of Mesenchymal Cell Apoptotic Process
Protein Phosphorylation
Cell Aging
Post-embryonic Development
Viral Process
Peptidyl-serine Phosphorylation
Negative Regulation Of Fibroblast Proliferation
Protein Stabilization
Maintenance Of Protein Location In Nucleus
Pathways
Drugs
Diseases
Other well-defined immunodeficiency syndromes, including the following seven diseases: Wiskott-Aldrich syndrome; DiGeorge syndrome; Hyper-IgE syndrome; X-linked lymphoproliferative syndrome; Immunodeficiency, Polyendocrinopathy, Enteropathy, X-linked Syndrome (IPEX); Cartilage-Hair Hypoplasia; Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED)
Conotruncal heart malformations, including: Double-outlet right ventricle; Persistent truncus arteriosus; Conotruncal anomaly face syndrome
Velocardiofacial syndrome
GWAS
Acute kidney injury in critical illness (
27576016
)
Adolescent idiopathic scoliosis (
31417091
)
Childhood ear infection (
27182965
28928442
)
DNA methylation (parent-of-origin) (
23725790
)
Interleukin-10 levels (
22205395
)
Myringotomy (
28928442
)
Prostate cancer (
25217961
)
Rheumatoid arthritis (
30891314
)
Schizophrenia (
26198764
)
Tonsillectomy (
27182965
28928442
)
Diastolic blood pressure (
30224653
)
Height (
31562340
)
Interacting Genes
5 interacting genes:
ERCC6
KPNA2
RNF216
SUMO2
UBC
Entrez ID
6899
23515
HPRD ID
09069
10316
Ensembl ID
ENSG00000184058
ENSG00000159256
Uniprot IDs
D9ZGG0
O43435
Q152R5
B4DHJ4
Q14149
Q4VBZ9
PDB IDs
4A04
4QQ4
5SVI
5SVX
5SVY
6O1E
6O5W
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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