TAGLN and CSF2

Data Source:
BioGRID (biochemical)

		TAGLN	CSF2
Description		transgelin	colony stimulating factor 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Extracellular Region Extracellular Space Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Actin Filament Binding	Cytokine Activity Granulocyte Macrophage Colony-stimulating Factor Receptor Binding Protein Binding Growth Factor Activity
	Biological Process	Muscle Organ Development Epithelial Cell Differentiation	MAPK Cascade Histamine Secretion Embryonic Placenta Development Immune Response Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Positive Regulation Of Macrophage Derived Foam Cell Differentiation Cytokine-mediated Signaling Pathway Myeloid Cell Differentiation Neutrophil Differentiation Monocyte Differentiation Macrophage Differentiation Positive Regulation Of Interleukin-23 Production Response To Silicon Dioxide Response To Fluid Shear Stress Epithelial Fluid Transport Macrophage Activation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Myeloid Dendritic Cell Differentiation Regulation Of Circadian Sleep/wake Cycle, Sleep Regulation Of Myeloid Cell Differentiation Negative Regulation Of Transcription, DNA-templated Cellular Response To Lipopolysaccharide Positive Regulation Of Podosome Assembly Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Dendritic Cell Differentiation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways			Interleukin-3, Interleukin-5 and GM-CSF signaling RAF/MAP kinase cascade Interleukin-10 signaling RUNX1 regulates transcription of genes involved in differentiation of myeloid cells Interleukin receptor SHC signaling
Drugs		Artenimol	KB002
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Blood protein levels ( 28240269) Breast cancer in childhood cancer survivors treated with more than 10 gray radiotherapy ( 29059430) Medication use (calcium channel blockers) ( 31015401) Refractive error ( 32231278)	Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Rheumatoid arthritis ( 30423114 22446963 24390342) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		8 interacting genes: ACD ACTA1 GORASP2 PIK3CD POT1 PRKCD RNF14 TINF2	7 interacting genes: CSF2RA CSF2RB IL3RA KITLG MEOX2 PRG2 SDC2
Entrez ID		6876	1437
HPRD ID		02891	00734
Ensembl ID		ENSG00000149591	ENSG00000164400
Uniprot IDs		Q01995 Q5U0D2	P04141
PDB IDs			1CSG 2GMF 4NKQ 4RS1 5C7X 5D70 5D71 5D72 6BFQ 6BFS
Enriched GO Terms of Interacting Partners?
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