BST2 and GATAD2A

Data Source:
BioGRID (biochemical)

		BST2	GATAD2A
Description		bone marrow stromal cell antigen 2	GATA zinc finger domain containing 2A
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GO Annotations	Cellular Component	Cytoplasm Multivesicular Body Golgi Apparatus Cytosol Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Apical Plasma Membrane Anchored Component Of Membrane Azurophil Granule Membrane Membrane Raft Extracellular Exosome	Nucleus Nucleoplasm NuRD Complex Nuclear Speck
	Molecular Function	RNA Binding Protein Binding Metalloendopeptidase Inhibitor Activity Identical Protein Binding Protein Homodimerization Activity	Protein Binding Zinc Ion Binding Protein-macromolecule Adaptor Activity Sequence-specific DNA Binding
	Biological Process	Negative Regulation Of Plasmacytoid Dendritic Cell Cytokine Production Response To Virus Negative Regulation Of Endopeptidase Activity Negative Regulation Of Cell Growth Negative Regulation Of Cell Migration Regulation Of Actin Cytoskeleton Organization Response To Interferon-gamma Response To Interferon-alpha Response To Interferon-beta B Cell Activation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Neutrophil Degranulation Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Type I Interferon Signaling Pathway Positive Regulation Of Leukocyte Proliferation Negative Regulation Of Intracellular Transport Of Viral Material	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation Negative Regulation Of Transcription, DNA-templated
Pathways		Neutrophil degranulation Interferon alpha/beta signaling	HDACs deacetylate histones ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression Regulation of TP53 Activity through Acetylation RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription Potential therapeutics for SARS
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Bipolar II disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body size at age 10 ( 32376654) Brain morphology (MOSTest) ( 32665545) Breast cancer ( 29059683) Breast cancer, ovarian cancer or prostate cancer (pleiotropy) ( 27432226) Height ( 25282103 31562340) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Nonalcoholic fatty liver disease ( 29385134) Platelet count ( 32888494) Plateletcrit ( 32888494) Pulse pressure ( 30578418) Red cell distribution width ( 28957414) Refractive error ( 32231278) Response to fenofibrate (LDL cholesterol levels) ( 27002377) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Schizophrenia ( 25056061 29483656 23974872) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Strenuous sports or other exercises ( 29899525) Type 2 diabetes ( 28869590)
Interacting Genes		3 interacting genes: CD81 HAGH HARS2	15 interacting genes: CBFA2T3 CREBBP H2AC20 H2BC21 H3C1 H4C1 KAT2B KRT32 KRT34 KRT40 MBD2 MBD3 MBD3L1 PAK4 SPOP
Entrez ID		684	54815
HPRD ID		02759	11741
Ensembl ID		ENSG00000130303	ENSG00000167491
Uniprot IDs		A0A024R7H5 Q10589	A0A024R7K7 A0A024R7M6 Q86YP4
PDB IDs		2LK9 2X7A 2XG7 3MQ7 3MQ9 3MQB 3MQC 3NWH 4P6Z 6CM9 6CRI 6D83 6D84 6DFF	2L2L
Enriched GO Terms of Interacting Partners?
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