BST1 and PCDH7

Data Source:
BioGRID (affinity chromatography technology)

		BST1	PCDH7
Description		bone marrow stromal cell antigen 1	protocadherin 7
Image
GO Annotations	Cellular Component	Uropod Extracellular Region Plasma Membrane Extrinsic Component Of Membrane Anchored Component Of Membrane Specific Granule Membrane Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Platelet Alpha Granule Membrane
	Molecular Function	NAD+ Nucleosidase Activity Transferase Activity Phosphorus-oxygen Lyase Activity NAD(P)+ Nucleosidase Activity NAD+ Nucleotidase, Cyclic ADP-ribose Generating ADP-ribosyl Cyclase Activity Cyclic ADP-ribose Hydrolase	Calcium Ion Binding
	Biological Process	Regulation Of Cell-matrix Adhesion Regulation Of Cellular Extravasation Humoral Immune Response Signal Transduction Positive Regulation Of Cell Population Proliferation NAD Metabolic Process Positive Regulation Of B Cell Proliferation Regulation Of Actin Cytoskeleton Organization Neutrophil Degranulation Regulation Of Inflammatory Response Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Calcium-mediated Signaling Regulation Of Neutrophil Chemotaxis Regulation Of Superoxide Metabolic Process Regulation Of Integrin-mediated Signaling Pathway	Platelet Degranulation Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
Pathways		Post-translational modification: synthesis of GPI-anchored proteins Nicotinate metabolism Neutrophil degranulation	Platelet degranulation
Drugs		Etheno-NAD Nicotinamide Adenosine 5'-[gamma-thio]triphosphate Nicotinamide Mononucleotide Etheno-Nadp
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Current cigarettes per day in chronic obstructive pulmonary disease ( 21685187) Parkinson's disease ( 22451204 21084426 21292315 19915576 25064009 32201043 27182965 32310270) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Response to beta blocker use in hypertension (systolic blood pressure) ( 31423876) Urinary metabolite levels in chronic kidney disease ( 31959995)	Adult body size ( 32376654) Adventurousness ( 30643258) Alzheimer's disease (late onset) ( 30820047) Attention deficit hyperactivity disorder ( 32279069) Body size at age 10 ( 32376654) Depressive symptom (sleep problems) (binary trait) ( 31530331) Diastolic blood pressure x smoking status (ever vs never) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Diffusing capacity of carbon monoxide ( 30694715) Electroencephalogram traits ( 25387704) Epilepsy ( 25087078) General risk tolerance (MTAG) ( 30643258) Generalized epilepsy ( 30531953) Hip circumference adjusted for BMI ( 28552196) Influenza A (H1N1) infection ( 26379185) Lipid traits ( 22028671) Mean arterial pressure x educational attainment (some college) interaction (2df) ( 32372009) Menarche (age at onset) ( 25231870) Mild influenza (H1N1) infection ( 26379185) Mouth morphology (principal component model) ( 30174134) Number of sexual partners ( 30643258) Obesity-related traits ( 23251661) Refractive astigmatism ( 25367360) Refractive error ( 32231278) Response to antipsychotic treatment in schizophrenia ( 29503163) Response to ziprazidone in schizophrenia ( 29503163) Smoking status (ever vs never smokers) ( 30643258) Underweight status ( 25133637) Very long-chain saturated fatty acid levels (fatty acid 22:0) ( 25378659) White matter hyperintensities in ischemic stroke ( 26674333)
Interacting Genes		2 interacting genes: CAV1 LBP	2 interacting genes: MTDH PPP1CA
Entrez ID		683	5099
HPRD ID		02665	04288
Ensembl ID		ENSG00000109743	ENSG00000169851
Uniprot IDs		Q10588	O60245
PDB IDs		1ISF 1ISG 1ISH 1ISI 1ISJ 1ISM	2YST
Enriched GO Terms of Interacting Partners?
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