RO60 and DSC2

Data Source:
BioGRID (two hybrid)

		RO60	DSC2
Description		Ro60, Y RNA binding protein	desmocollin 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Ribonucleoprotein Complex	Cornified Envelope Plasma Membrane Cell-cell Junction Adherens Junction Intercalated Disc Integral Component Of Membrane Desmosome Cytoplasmic Vesicle Extracellular Exosome
	Molecular Function	RNA Binding U2 SnRNA Binding Metal Ion Binding	Calcium Ion Binding Protein Binding Cell Adhesive Protein Binding Involved In Bundle Of His Cell-Purkinje Myocyte Communication
	Biological Process	Immune System Development Transcription By RNA Polymerase III Smoothened Signaling Pathway Response To UV Regulation Of Gene Expression Cellular Response To Interferon-alpha Cilium Assembly	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cellular Response To Starvation Keratinization Cornification Cardiac Muscle Cell-cardiac Muscle Cell Adhesion Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication Regulation Of Heart Rate By Cardiac Conduction Cell-cell Adhesion Regulation Of Ventricular Cardiac Muscle Cell Action Potential
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases			Arrhythmogenic right ventricular cardiomyopathy (ARVC)
GWAS			Blood protein levels ( 30072576 29875488) Bronchopulmonary dysplasia ( 23897914) Metabolite levels ( 23823483)
Interacting Genes		6 interacting genes: CDC42 DDX6 RAB11FIP5 RNY1 RNY3 TRIM21	6 interacting genes: CLK1 DSG1 DSG2 JUP PKP2 PKP3
Entrez ID		6738	1824
HPRD ID		15964	00512
Ensembl ID		ENSG00000116747	ENSG00000134755
Uniprot IDs		A0A024R983 G5E9R9 P10155	A0A3B3ISU0 Q02487
PDB IDs			5ERP 5J5J
Enriched GO Terms of Interacting Partners?
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