SRP54 and PRORP

Data Source:
BioGRID (affinity chromatography technology)

		SRP54	PRORP
Description		signal recognition particle 54	protein only RNase P catalytic subunit
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GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Endoplasmic Reticulum Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Nuclear Speck	Nucleoplasm Mitochondrion Mitochondrial Matrix Mitochondrial Ribonuclease P Complex
	Molecular Function	RNA Binding GTPase Activity Protein Binding GTP Binding 7S RNA Binding GDP Binding Endoplasmic Reticulum Signal Peptide Binding Ribonucleoprotein Complex Binding	Ribonuclease P Activity Metal Ion Binding
	Biological Process	SRP-dependent Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition Neutrophil Chemotaxis Granulocyte Differentiation Exocrine Pancreas Development Protein Targeting To ER	TRNA 5'-leader Removal Mitochondrial TRNA Methylation RNA Phosphodiester Bond Hydrolysis, Endonucleolytic Mitochondrial TRNA Processing Mitochondrial TRNA 5'-end Processing
Pathways		SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane	tRNA processing in the mitochondrion tRNA modification in the mitochondrion rRNA processing in the mitochondrion
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Immunoglobulin light chain (AL) amyloidosis ( 28025584)
Interacting Genes		2 interacting genes: RNPS1 SRP19
Entrez ID		6729	9692
HPRD ID		05330	18711
Ensembl ID		ENSG00000100883	ENSG00000100890
Uniprot IDs		P61011	O15091
PDB IDs		1MFQ 1QB2 5L3Q 6Y2Z 6Y30 6Y31 6Y32	4ROU 4XGL 4XGM
Enriched GO Terms of Interacting Partners?
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