SRP54 and TKTL1

Data Source:
BioGRID (biochemical)

		SRP54	TKTL1
Description		signal recognition particle 54	transketolase like 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Endoplasmic Reticulum Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Nuclear Speck	Nucleus Cytosol
	Molecular Function	RNA Binding GTPase Activity Protein Binding GTP Binding 7S RNA Binding GDP Binding Endoplasmic Reticulum Signal Peptide Binding Ribonucleoprotein Complex Binding	Transketolase Activity Thiamine Pyrophosphate Binding Metal Ion Binding
	Biological Process	SRP-dependent Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition Neutrophil Chemotaxis Granulocyte Differentiation Exocrine Pancreas Development Protein Targeting To ER	Glucose Catabolic Process Thiamine Metabolic Process
Pathways		SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Immunoglobulin light chain (AL) amyloidosis ( 28025584)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Red blood cell traits ( 23446634) Refractive error ( 32231278) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Testicular germ cell tumor ( 28604732)
Interacting Genes		2 interacting genes: RNPS1 SRP19
Entrez ID		6729	8277
HPRD ID		05330	02080
Ensembl ID		ENSG00000100883	ENSG00000007350
Uniprot IDs		P61011	B7Z7I0 P51854
PDB IDs		1MFQ 1QB2 5L3Q 6Y2Z 6Y30 6Y31 6Y32
Enriched GO Terms of Interacting Partners?
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