SRP54 and KLK12

Data Source:
BioGRID (genetic interference)

		SRP54	KLK12
Description		signal recognition particle 54	kallikrein related peptidase 12
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Endoplasmic Reticulum Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Nuclear Speck	Extracellular Region Extracellular Space Secretory Granule
	Molecular Function	RNA Binding GTPase Activity Protein Binding GTP Binding 7S RNA Binding GDP Binding Endoplasmic Reticulum Signal Peptide Binding Ribonucleoprotein Complex Binding	Serine-type Endopeptidase Activity Peptidase Activity Serine-type Peptidase Activity
	Biological Process	SRP-dependent Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition Neutrophil Chemotaxis Granulocyte Differentiation Exocrine Pancreas Development Protein Targeting To ER	Proteolysis Cornification
Pathways		SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane	Formation of the cornified envelope
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Immunoglobulin light chain (AL) amyloidosis ( 28025584)	Blood protein levels ( 29875488 28240269)
Interacting Genes		2 interacting genes: RNPS1 SRP19
Entrez ID		6729	43849
HPRD ID		05330	05705
Ensembl ID		ENSG00000100883	ENSG00000186474
Uniprot IDs		P61011	A0A024R4M4 B9EGA9 Q9UKR0
PDB IDs		1MFQ 1QB2 5L3Q 6Y2Z 6Y30 6Y31 6Y32
Enriched GO Terms of Interacting Partners?
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