SRD5A2 and ATP5MG

Data Source:
BioGRID (affinity chromatography technology)

		SRD5A2	ATP5MG
Description		steroid 5 alpha-reductase 2	ATP synthase membrane subunit g
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Mitochondrial Proton-transporting ATP Synthase Complex, Coupling Factor F(o) Mitochondrion Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex
	Molecular Function	3-oxo-5-alpha-steroid 4-dehydrogenase Activity Protein Binding Sterol 5-alpha Reductase Activity Oxidoreductase Activity Testosterone Dehydrogenase [NAD(P)] Activity Cholestenone 5-alpha-reductase Activity	Protein Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism
	Biological Process	Steroid Biosynthetic Process Androgen Biosynthetic Process Cell-cell Signaling Androgen Metabolic Process Male Gonad Development Cell Differentiation Male Genitalia Development Testosterone Biosynthetic Process	ATP Biosynthetic Process ATP Synthesis Coupled Proton Transport Cristae Formation Mitochondrial ATP Synthesis Coupled Proton Transport
Pathways		Androgen biosynthesis	Formation of ATP by chemiosmotic coupling Cristae formation
Drugs		Spironolactone Azelaic acid Dutasteride Finasteride	Artenimol Phenethyl Isothiocyanate
Diseases		46,XY disorders of sex development (Disorders in androgen synthesis or action), including: Congenital adrenal hyperplasias; Leydig cell hypoplasia; Androgen insensitivity syndrome (AIS)
GWAS		Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Idiopathic pulmonary fibrosis ( 29066090) Inflammatory biomarkers ( 24182552) Male-pattern baldness ( 29146897 27182965 28196072) Zinc levels ( 26025379)
Interacting Genes		2 interacting genes: CYSRT1 GNMT	2 interacting genes: MAGEC1 RHOU
Entrez ID		6716	10632
HPRD ID		07390	09815
Ensembl ID		ENSG00000277893	ENSG00000167283
Uniprot IDs		P31213	O75964
PDB IDs		7BW1
Enriched GO Terms of Interacting Partners?
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