SPP2 and PIGS

		SPP2	PIGS
Description		secreted phosphoprotein 2	phosphatidylinositol glycan anchor biosynthesis class S
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Lumen Platelet Dense Granule Lumen Collagen-containing Extracellular Matrix	Endoplasmic Reticulum Membrane Membrane GPI-anchor Transamidase Complex
	Molecular Function	Endopeptidase Inhibitor Activity	Protein Binding
	Biological Process	Skeletal System Development Platelet Degranulation Negative Regulation Of Endopeptidase Activity Post-translational Protein Modification Cellular Protein Metabolic Process Bone Remodeling	Attachment Of GPI Anchor To Protein
Pathways		Platelet degranulation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Attachment of GPI anchor to uPAR
Drugs
Diseases
GWAS		Cognitive decline (age-related) ( 28078323) Hair greying ( 26926045) Osteoporosis-related phenotypes ( 20548944) Triglyceride levels ( 30108155)
Interacting Genes			14 interacting genes: CPEB2 KRT40 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP19-2 KRTAP2-3 KRTAP2-4 KRTAP6-3 KRTAP9-2 NBPF19 NOTCH2NLA TRIP6
Entrez ID		6694	94005
HPRD ID		04029	15135
Ensembl ID		ENSG00000072080	ENSG00000087111
Uniprot IDs		Q13103	Q8NBL9 Q96IR5 Q96S52
PDB IDs
Enriched GO Terms of Interacting Partners?
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