DDRGK1 and FASTKD5

Data Source:
BioGRID (affinity chromatography technology)

		DDRGK1	FASTKD5
Description		DDRGK domain containing 1	FAST kinase domains 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane	Mitochondrion Ribonucleoprotein Granule Mitochondrial Nucleoid
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Protein Binding Ubiquitin-like Protein Ligase Binding	RNA Binding Protein Binding RRNA Binding
	Biological Process	Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Cell Migration Regulation Of Protein Stability Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Endoplasmic Reticulum Stress Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of NF-kappaB Transcription Factor Activity Cartilage Development Reticulophagy Protein Localization To Endoplasmic Reticulum Protein Ufmylation Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of I-kappaB Phosphorylation Negative Regulation Of IRE1-mediated Unfolded Protein Response Positive Regulation Of Metallopeptidase Activity Positive Regulation Of Protein Localization To Endoplasmic Reticulum Positive Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Protein K69-linked Ufmylation	Mitochondrial RNA Processing MRNA Processing Regulation Of Mitochondrial MRNA Stability
Pathways
Drugs
Diseases
GWAS		HDL cholesterol levels x loop diuretics use interaction ( 31806883) Night sleep phenotypes ( 27126917) Parkinson's disease ( 25064009 28892059) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Response to hepatitis C treatment ( 21659334) Ribavirin-induced anemia ( 20637204)	Household income ( 31844048) Household income (MTAG) ( 31844048) Night sleep phenotypes ( 27126917)
Interacting Genes		3 interacting genes: APP FBXO7 HTR6	5 interacting genes: CCDC85B KCNH1 MID2 MTUS2 TRIM27
Entrez ID		65992	60493
HPRD ID		12741	07813
Ensembl ID		ENSG00000198171	ENSG00000215251
Uniprot IDs		Q96HY6	Q7L8L6
PDB IDs
Enriched GO Terms of Interacting Partners?
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