SLCO2A1 and IFT122

Data Source:
BioGRID (genetic interference)

		SLCO2A1	IFT122
Description		solute carrier organic anion transporter family member 2A1	intraflagellar transport 122
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane	Cytoplasm Cilium Membrane Intraciliary Transport Particle A Photoreceptor Connecting Cilium Ciliary Basal Body Ciliary Tip Non-motile Cilium
	Molecular Function	Lipid Transporter Activity Prostaglandin Transmembrane Transporter Activity Sodium-independent Organic Anion Transmembrane Transporter Activity	Protein Binding
	Biological Process	Lipid Transport Prostaglandin Transport Sodium-independent Organic Anion Transport Transmembrane Transport	Neural Tube Closure Embryonic Body Morphogenesis Embryonic Heart Tube Development Intraciliary Retrograde Transport Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Negative Regulation Of Smoothened Signaling Pathway Camera-type Eye Morphogenesis Limb Development Cilium Assembly Protein Localization To Cilium Non-motile Cilium Assembly
Pathways		Defective SLCO2A1 causes primary, autosomal recessive hypertrophic osteoarthropathy 2 (PHOAR2) Transport of organic anions	Hedgehog 'off' state Intraflagellar transport
Drugs
Diseases			Cranioectodermal dysplasia
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Colorectal cancer ( 30529582) Height ( 31562340)	Diisocyanate-induced asthma ( 25918132) Systemic sclerosis (anti-topoisomerase-positive) ( 29293537) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes
Entrez ID		6578	55764
HPRD ID		03269	06922
Ensembl ID		ENSG00000174640	ENSG00000163913
Uniprot IDs		Q92959	B3KUD1 B4DST2 Q9HBG6
PDB IDs		3MRR
Enriched GO Terms of Interacting Partners?
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