SLC6A9 and NAPA

Data Source:
BioGRID (proximity labelling technology)

		SLC6A9	NAPA
Description		solute carrier family 6 member 9	NSF attachment protein alpha
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Plasma Membrane Integral Component Of Plasma Membrane Basal Plasma Membrane Postsynaptic Density Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane Integral Component Of Synaptic Vesicle Membrane Dense Core Granule Hippocampal Mossy Fiber To CA3 Synapse Parallel Fiber To Purkinje Cell Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane	Golgi Membrane Vacuolar Membrane Cytosol Plasma Membrane Membrane SNARE Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Extracellular Exosome Presynapse Postsynapse Glutamatergic Synapse
	Molecular Function	Glycine Transmembrane Transporter Activity Glycine:sodium Symporter Activity	SNARE Binding Soluble NSF Attachment Protein Activity Protein Binding Syntaxin Binding Protein-containing Complex Binding
	Biological Process	Neurotransmitter Transport Glycine Transport Sodium Ion Transmembrane Transport Positive Regulation Of Hemoglobin Biosynthetic Process Positive Regulation Of Heme Biosynthetic Process Transport Across Blood-brain Barrier Glycine Import Across Plasma Membrane Positive Regulation Of Iron Ion Transmembrane Transporter Activity Positive Regulation Of Iron Ion Import Across Plasma Membrane Negative Regulation Of NMDA Glutamate Receptor Activity	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Brain Development Regulation Of Synaptic Vesicle Priming Synaptic Vesicle Priming Neuron Differentiation Positive Regulation Of ATPase Activity Synaptic Transmission, Glutamatergic SNARE Complex Disassembly Apical Protein Localization COPII Vesicle Coating Membrane Fusion
Pathways		Na+/Cl- dependent neurotransmitter transporters	COPII-mediated vesicle transport Golgi Associated Vesicle Biogenesis COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder or cannabis use ( 30610198) Autism spectrum disorder or schizophrenia ( 28540026) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 29403010 32888494) Refractive error ( 32231278)	Blood protein levels ( 30072576)
Interacting Genes		3 interacting genes: GABRR1 PRKCA STX1A	18 interacting genes: APP BNIP1 GNA12 GOSR1 GOSR2 HSPB1 NSF RTN4 SNAP23 SNAP25 STX12 STX1A STX4 STX5 STX7 STX8 TRPC3 VAMP8
Entrez ID		6536	8775
HPRD ID		03010	04447
Ensembl ID		ENSG00000196517	ENSG00000105402
Uniprot IDs		B7Z3W8 B7Z589 P48067	A0A024R0R9 P54920
PDB IDs
Enriched GO Terms of Interacting Partners?
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