SIM2 and MAST3

Data Source:
HPRD (in vivo)

		SIM2	MAST3
Description		SIM bHLH transcription factor 2	microtubule associated serine/threonine kinase 3
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm Nuclear Body
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Heterodimerization Activity	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Nervous System Development Embryonic Pattern Specification Cell Differentiation Lung Development	Cytoskeleton Organization Peptidyl-serine Phosphorylation Intracellular Signal Transduction
Pathways
Drugs
Diseases
GWAS		Asthma and hay fever ( 24388013) Cerebellum cortex volume ( 31530798) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Night sleep phenotypes ( 27126917) Red blood cell count ( 27863252)	Adult body size ( 32376654) Body fat mass ( 28552196) Eosinophil percentage of white cells ( 32888494) Glycine levels ( 30837465) Mental health study participation (completed survey) ( 31263887) Number of sexual partners ( 30643258) Red cell distribution width ( 32888494) Urate levels ( 31578528)
Interacting Genes		4 interacting genes: ARNT ARNT2 MAGED1 PRKN	2 interacting genes: CNTNAP4 PTEN
Entrez ID		6493	23031
HPRD ID		02935	19403
Ensembl ID		ENSG00000159263	ENSG00000099308
Uniprot IDs		Q14190	O60307
PDB IDs			1V9V 3KHF
Enriched GO Terms of Interacting Partners?
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