CRTC3 and HAPLN3

Data Source:
BioGRID (two hybrid)

		CRTC3	HAPLN3
Description		CREB regulated transcription coactivator 3	hyaluronan and proteoglycan link protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Extracellular Space Extracellular Matrix
	Molecular Function	Protein Binding CAMP Response Element Binding Protein Binding	Hyaluronic Acid Binding
	Biological Process	Viral Process Positive Regulation Of CREB Transcription Factor Activity Macrophage Activation Negative Regulation Of CAMP-mediated Signaling Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Lipid Catabolic Process Protein Homotetramerization Energy Homeostasis	Skeletal System Development Cell Adhesion Central Nervous System Development
Pathways		Transcriptional activation of mitochondrial biogenesis Circadian Clock
Drugs			Hyaluronic acid
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Chromium levels ( 26025379) Chronic postoperative pain ( 31903573) Colorectal cancer ( 29228715) Daytime sleep phenotypes ( 27126917) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Gastroesophageal reflux disease ( 27485664) Heel bone mineral density ( 28869591) Inflammatory bowel disease ( 28067908 23128233) Information processing speed ( 21130836) Male-pattern baldness ( 28196072) Offspring birth weight ( 31043758) Response to exercise (triglyceride level interaction) ( 26491034) Ulcerative colitis ( 28067908)	Appendicular lean mass ( 33097823) Blood protein levels ( 28240269) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Height ( 31562340) Lung cancer in ever smokers ( 28604730) Multiple keratinocyte cancers ( 28081215)
Interacting Genes		4 interacting genes: CA13 KLHL12 SIK2 YWHAG
Entrez ID		64784	145864
HPRD ID		13384	13629
Ensembl ID		ENSG00000140577	ENSG00000140511
Uniprot IDs		Q6UUV7 Q8TEF4	A0A024RC58 A8K7T8 H3BTH8 Q96S86
PDB IDs
Enriched GO Terms of Interacting Partners?
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