MRPS25 and HDAC11

Data Source:
HPRD (two hybrid, in vitro)

		MRPS25	HDAC11
Description		mitochondrial ribosomal protein S25	histone deacetylase 11
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Ribosome	Histone Deacetylase Complex Nucleus Plasma Membrane
	Molecular Function	Structural Constituent Of Ribosome	Histone Deacetylase Activity Protein Binding Transcription Factor Binding NAD-dependent Histone Deacetylase Activity (H3-K14 Specific)
	Biological Process	Mitochondrial Translational Elongation Mitochondrial Translational Termination	Chromatin Organization Oligodendrocyte Development Histone Deacetylation Histone H3 Deacetylation
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination	NOTCH1 Intracellular Domain Regulates Transcription Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Notch-HLH transcription pathway
Drugs			Belinostat Panobinostat
Diseases
GWAS			Body mass index ( 26426971) Height ( 20881960) Hip circumference adjusted for BMI ( 25673412) Ulcerative colitis ( 26278503)
Interacting Genes		1 interacting genes: ERCC6	7 interacting genes: CDC25A CDKN1A HDAC6 MAPK6 NELFCD NRM PHYHIP
Entrez ID		64432	79885
HPRD ID		17594	09146
Ensembl ID		ENSG00000131368	ENSG00000163517
Uniprot IDs		P82663	B5MCQ6 E7ETT9 Q6IA14 Q96DB2
PDB IDs		3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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