CLEC11A and STARD3

Data Source:
HPRD (in vitro, two hybrid)

		CLEC11A	STARD3
Description		C-type lectin domain containing 11A	StAR related lipid transfer domain containing 3
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm	Nucleoplasm Cytoplasm Lysosomal Membrane Endosome Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle Organelle Membrane Contact Site Endoplasmic Reticulum-endosome Membrane Contact Site
	Molecular Function	Protein Binding Growth Factor Activity Carbohydrate Binding	Protein Binding Cholesterol Binding Protein Homodimerization Activity Cholesterol Transfer Activity
	Biological Process	Ossification Signal Transduction Positive Regulation Of Cell Population Proliferation	Lipid Metabolic Process C21-steroid Hormone Biosynthetic Process Mitochondrial Transport Steroid Metabolic Process Cholesterol Metabolic Process Cholesterol Transport Vesicle Tethering To Endoplasmic Reticulum Intermembrane Lipid Transfer
Pathways			Pregnenolone biosynthesis
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Carotid plaque maximum area ( 32469969) Dietary fat liking ( 32516399) Stem cell growth factor beta levels ( 27989323) Sum of carotid plaque area ( 32469969) Sum of stenosis ( 32469969)	Alcohol consumption ( 31358974) Apolipoprotein A1 levels ( 32203549) Asthma ( 31959851 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) HDL cholesterol ( 24097068 20686565) HDL cholesterol levels ( 32203549 28334899 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Hemoglobin levels ( 32327693) Menopause (age at onset) ( 26414677) Pancreatic ductal adenocarcinoma ( 30541042) Refractive error ( 32231278) Smoking behaviour (cigarettes smoked per day) ( 30679032) Triglyceride levels ( 30108155) Ulcerative colitis ( 20228799)
Interacting Genes		2 interacting genes: KITLG UBQLN2	6 interacting genes: AQP6 CREB3 DAPK1 GOPC LMNA RNF170
Entrez ID		6320	10948
HPRD ID		05277	06132
Ensembl ID		ENSG00000105472	ENSG00000131748
Uniprot IDs		Q9Y240	Q14849
PDB IDs			1EM2 2I92 5I9J
Enriched GO Terms of Interacting Partners?
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